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Croda International Plc ceramide sphingoid internal standard mixture ii
Ceramide Sphingoid Internal Standard Mixture Ii, supplied by Croda International Plc, used in various techniques. Bioz Stars score: 95/100, based on 81 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ceramide+sphingoid+internal+standard+mixture+ii/Cer%2FSph+Mixture+II/10__1016_slash_j__fbio__2026__108829-49-1-13
Average 95 stars, based on 81 article reviews
ceramide sphingoid internal standard mixture ii - by Bioz Stars, 2026-09
95/100 stars

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Concentration Assay:

Article Title: Protective roles of adiponectin and molecular signatures of HNF4α and PPARα as downstream targets of adiponectin in pancreatic β cells
Article Snippet: .. Immediately afterwards, 20 μL of organic internal standard solution was added (Ceramide/Sphingoid Internal Standard Mixture II diluted 1:10 in ethanol methanol combined with a mixture of C16 Ceramide-d7 (d18:1-d7/16:0), C18 Ceramide-d7 (d18:1-d7/18:0), C24 Ceramide-d7 (d18:1-d7/24:0), and C24:1 Ceramide-d7 (d18:1-d7/24:1(15Z)) at a concentration of 2.4 μM, Avanti Polar Lipids, Alabaster, AL). ..

Article Title: FGF21 promotes longevity in diet-induced obesity through metabolic benefits independent of growth suppression.
Article Snippet: In brief This study demonstrates that inducible, adipocyte-specific overexpression of FGF21 in adult male mice improves metabolic health and extends lifespan during high-fat diet feeding.. These benefits occur independently of growth suppression and are associated with reduced visceral adipose inflammation and ceramide levels, offering mechanistic insights into FGF21’s pro-longevity effects under metabolic stress.

Article Title: Defining lipedema's molecular hallmarks by multi-omics approach for disease prediction in women.
Article Snippet: .. Immediately afterward, 20 μl internal standard solution was added (Ceramide/Sphingoid Internal Standard Mixture II at a 10 fold dilution in methanol combined with a mixture of C16 ceramide-d7 (d18:1-d7/16:0), C18 ceramide-d7 (d18:1-d7/18:0), C24 ceramide-d7 (d18:1-d7/24:0), and C24:1 ceramide-d7 (d18:1-d7/24:1(15Z)) at a concentration of 2.4 μM; Avanti Polar Lipids, Alabaster, AL). ..

Article Title: Protective roles of adiponectin and molecular signatures of HNF4α and PPARα as downstream targets of adiponectin in pancreatic β cells.
Article Snippet: .. Immediately afterwards, 20 mL of organic internal standard solution was added (Ceramide/Sphingoid Internal Standard Mixture II diluted 1:10 in ethanol methanol combined with a mixture of C16 Ceramide-d7 (d18:1-d7/16:0), C18 Ceramide-d7 (d18:1-d7/18:0), C24 Ceramide-d7 (d18:1-d7/24:0), and C24:1 Ceramide-d7 (d18:1-d7/ 24:1(15Z)) at a concentration of 2.4 mM, Avanti Polar Lipids, Alabaster, AL). ..

Milk:

Article Title: The mTORC2 subunit RICTOR drives breast cancer progression by promoting ganglioside biosynthesis through transcriptional and epigenetic mechanisms.
Article Snippet: Methanol (MS Grade Cat#34966), Honeywell, USA, Chloroform (MS Grade Cat#25669-1L), Honeywell, USA, 2-Propanol (Cat#34965), Honeywell, USA, Formic Acid (MS Grade Cat# 56302-50ML), Fluka, USA, Ammonium formate, (Cat# 14266-25G), Honeywell Fluka, USA, Acetonitrile (Cat#34967) Honeywell, USA, Ammonium acetate (Cat#14267-25G), Honeywell, USA, Ammonium hydroxide (Cat# 16227), Thermo Fisher, USA, Triethyl ammonium bicarbonate buffer Sodium Hydroxide (Cat# T70408), Sigma, USA, Sodium Hydroxide (Cat# 13913) SRL Chem, India, Chymotrypsin (Cat# 11418467001), Merck, USA, Water (MS Grade Cat#39253-4L) Riedel-de haen, Germany. .. Potassium hydroxide (Cat#84749), Sisco Research, India, Iodoacetamide (Cat# 144-48-9) Sigma, USA, Glacial acetic acid (Cat# 144-48-9) Merck, USA, Digitonin (Cat# D141) Sigma, USA, ACQUITY UPLC BEH Shield RP18 column PLOS Biology | https://doi.org/10.1371/journal.pbio.3003362 September 11, 2025 22 / 35 (Cat#186002854) Water Ltd., ChromXP C18-CL trap column (Cat#5016752) was purchased from Eksigent, ABSciex, USA, nanoViper C18 column (Cat# 164569) Thermo Scientific, USA, Kinetex C18 column (Cat#00B-4601-AN) Phenomenex, USA, Ceramide/Sphingoid Internal Standard Mixture II (Cat# LM6005-1EA) Avanti Polar Lipids, USA, C18 Ganglioside GM3-d3 (d18:1/18:0d3) (ammonium salt) (Cat# 24850) Cayman Chemicals, USA, Ganglioside GM3 (Bovine Milk) (Cat# 860058P) Avanti Polar Lipids, USA, Ganglioside GM1 (Bovine Brain) (Cat# 860065P) Avanti Polar Lipids, USA, Ganglioside GD3 (Bovine Milk) (Cat# 860060P) Avanti Polar Lipids, USA, FITC labeled cholera toxin B (Cat#1,655) Sigma-Aldrich, USA. ..

Article Title: The mTORC2 subunit RICTOR drives breast cancer progression by promoting ganglioside biosynthesis through transcriptional and epigenetic mechanisms
Article Snippet: Methanol (MS Grade Cat#34966), Honeywell, USA, Chloroform (MS Grade Cat#25669-1L), Honeywell, USA, 2-Propanol (Cat#34965), Honeywell, USA, Formic Acid (MS Grade Cat# 56302-50ML), Fluka, USA, Ammonium formate, (Cat# 14266-25G), Honeywell Fluka, USA, Acetonitrile (Cat#34967) Honeywell, USA, Ammonium acetate (Cat#14267-25G), Honeywell, USA, Ammonium hydroxide (Cat# 16227), Thermo Fisher, USA, Triethyl ammonium bicarbonate buffer Sodium Hydroxide (Cat# T70408 ), Sigma, USA, Sodium Hydroxide (Cat# 13913) SRL Chem, India, Chymotrypsin (Cat# 11418467001), Merck, USA, Water (MS Grade Cat#39253-4L) Riedel-de haen, Germany. .. Potassium hydroxide (Cat#84749), Sisco Research, India, Iodoacetamide (Cat# 144-48-9) Sigma, USA, Glacial acetic acid (Cat# 144-48-9) Merck, USA, Digitonin (Cat# D141) Sigma, USA, ACQUITY UPLC BEH Shield RP18 column (Cat#186002854) Water Ltd., ChromXP C18-CL trap column (Cat#5016752) was purchased from Eksigent, ABSciex, USA, nanoViper C18 column (Cat# 164569) Thermo Scientific, USA, Kinetex C18 column (Cat#00B-4601-AN) Phenomenex, USA, Ceramide/Sphingoid Internal Standard Mixture II (Cat# LM6005-1EA) Avanti Polar Lipids, USA, C18 Ganglioside GM3-d3 (d18:1/18:0d3) (ammonium salt) (Cat# 24850) Cayman Chemicals, USA, Ganglioside GM3 (Bovine Milk) (Cat# 860058P) Avanti Polar Lipids, USA, Ganglioside GM1 (Bovine Brain) (Cat# 860065P) Avanti Polar Lipids, USA, Ganglioside GD3 (Bovine Milk) (Cat# 860060P) Avanti Polar Lipids, USA, FITC labeled cholera toxin B (Cat#1,655) Sigma-Aldrich, USA. .. Ceramide Glucosyl transferase (Cat#ab124296) Abcam, UK, Ceramide Glucosyl transferase IHC (Cat# ab197369) Abcam, UK, Ceramide Glucosyl transferase (Cat# 12869-1-AP) ProteinTech, USA, GBA1 (Cat# ab88300) Abcam, UK, eIF4EBP1 (Cat# ab32024) Abcam, UK, P-eIF4EBP1 (Cat# ab75767) Abcam, UK, DNMT1 (Cat# ab188453) Abcam, UK, DNMT1 (Cat# MA5-16169) Invitrogen, USA, H3K4ME3 (Cat# ab1791) Abcam, UK, H3 (Cat# ab8580) Abcam, UK, Rictor (Cat# 2140S) Cell Signaling, USA, Raptor (Cat# 2280) Cell Signaling, USA, Akt (Cat# 4685) Cell Signaling, USA, P- Akt (Cat# 4060) Cell Signaling, USA, P-SGK1 (Cat# 5599) Cell Signaling, USA, P70 Kinase (Cat# 5599) Cell Signaling, USA, ZFX (Cat# 5419) Cell Signaling, USA, ZFX (Cat# PA5-78234) Abcam, UK, JARID1A (KDM5A) (Cat# 3876S) Cell Signaling, USA, KDM5A (Cat# ab70892), Abcam, UK, Phosphoserine (Cat# ab9332) Abcam, UK, EGFR (Cat# 2232) Cell Signaling, USA, P-EGFR (1068) (Cat# 2232) Cell Signaling, USA, P-EGFR(1178) (Cat# 2234) Cell Signaling, USA, Erk1/2 (Cat# 9102S) Cell Signaling, USA, P- Erk1/2 (Cat# 9101) Cell Signaling, USA, Anti-ceramide antibody (Cat# C8104) Sigma, USA, GM3 Synthase (ST8SIA-V) (Cat# sc-365329) Santa Cruz, USA, B3GALT4 (Cat# ab169759) Abcam, UK, GM2/GD2 Synthase (B4GALNT1) (Cat# sc-376505) Santa Cruz, USA, NEU1 (Cat# 67032-1-Ig) ProteinTech, USA, NEU2 (Cat# 24523-1-AP), ProteinTech, USA, NEU3 (Cat# 27879-I-AP), ProteinTech, USA, NEU4 (Cat# 12995-I-AP) ProteinTech, USA, HEXA (Cat# 60337-I-Ig) ProteinTech, USA, HEXB (Cat# 16229-I-AP), ProteinTech, USA, GLA (Cat# 66121-I-Ig), ProteinTech, USA, GLB (Cat# 66586-I-Ig) ProteinTech, USA, β-actin, (Cat# A5441), Sigma, USA, β-actin (Cat# 66009-1-Ig), ProteinTech, USA, Secondary IgG anti-mouse Alexa fluor 594 (Cat# 88903) Cell Signaling, USA, FITC anti-mouse IgM (Cat# 406506) BioLegend, USA, Goat anti-mouse IgG (L+H) (Cat#ab6789) Abcam, UK, Goat anti-rabbit IgG-HRP (Cat# sc-2004) Santa Cruz, USA, Rabbit IgG isotype control (Cat# 02-6102), Invitrogen, USA, Mouse IgG2a Isotype Control (Cat# 02-6200) Invitrogen, USA.

Labeling:

Article Title: The mTORC2 subunit RICTOR drives breast cancer progression by promoting ganglioside biosynthesis through transcriptional and epigenetic mechanisms.
Article Snippet: Methanol (MS Grade Cat#34966), Honeywell, USA, Chloroform (MS Grade Cat#25669-1L), Honeywell, USA, 2-Propanol (Cat#34965), Honeywell, USA, Formic Acid (MS Grade Cat# 56302-50ML), Fluka, USA, Ammonium formate, (Cat# 14266-25G), Honeywell Fluka, USA, Acetonitrile (Cat#34967) Honeywell, USA, Ammonium acetate (Cat#14267-25G), Honeywell, USA, Ammonium hydroxide (Cat# 16227), Thermo Fisher, USA, Triethyl ammonium bicarbonate buffer Sodium Hydroxide (Cat# T70408), Sigma, USA, Sodium Hydroxide (Cat# 13913) SRL Chem, India, Chymotrypsin (Cat# 11418467001), Merck, USA, Water (MS Grade Cat#39253-4L) Riedel-de haen, Germany. .. Potassium hydroxide (Cat#84749), Sisco Research, India, Iodoacetamide (Cat# 144-48-9) Sigma, USA, Glacial acetic acid (Cat# 144-48-9) Merck, USA, Digitonin (Cat# D141) Sigma, USA, ACQUITY UPLC BEH Shield RP18 column PLOS Biology | https://doi.org/10.1371/journal.pbio.3003362 September 11, 2025 22 / 35 (Cat#186002854) Water Ltd., ChromXP C18-CL trap column (Cat#5016752) was purchased from Eksigent, ABSciex, USA, nanoViper C18 column (Cat# 164569) Thermo Scientific, USA, Kinetex C18 column (Cat#00B-4601-AN) Phenomenex, USA, Ceramide/Sphingoid Internal Standard Mixture II (Cat# LM6005-1EA) Avanti Polar Lipids, USA, C18 Ganglioside GM3-d3 (d18:1/18:0d3) (ammonium salt) (Cat# 24850) Cayman Chemicals, USA, Ganglioside GM3 (Bovine Milk) (Cat# 860058P) Avanti Polar Lipids, USA, Ganglioside GM1 (Bovine Brain) (Cat# 860065P) Avanti Polar Lipids, USA, Ganglioside GD3 (Bovine Milk) (Cat# 860060P) Avanti Polar Lipids, USA, FITC labeled cholera toxin B (Cat#1,655) Sigma-Aldrich, USA. ..

Article Title: The mTORC2 subunit RICTOR drives breast cancer progression by promoting ganglioside biosynthesis through transcriptional and epigenetic mechanisms
Article Snippet: Methanol (MS Grade Cat#34966), Honeywell, USA, Chloroform (MS Grade Cat#25669-1L), Honeywell, USA, 2-Propanol (Cat#34965), Honeywell, USA, Formic Acid (MS Grade Cat# 56302-50ML), Fluka, USA, Ammonium formate, (Cat# 14266-25G), Honeywell Fluka, USA, Acetonitrile (Cat#34967) Honeywell, USA, Ammonium acetate (Cat#14267-25G), Honeywell, USA, Ammonium hydroxide (Cat# 16227), Thermo Fisher, USA, Triethyl ammonium bicarbonate buffer Sodium Hydroxide (Cat# T70408 ), Sigma, USA, Sodium Hydroxide (Cat# 13913) SRL Chem, India, Chymotrypsin (Cat# 11418467001), Merck, USA, Water (MS Grade Cat#39253-4L) Riedel-de haen, Germany. .. Potassium hydroxide (Cat#84749), Sisco Research, India, Iodoacetamide (Cat# 144-48-9) Sigma, USA, Glacial acetic acid (Cat# 144-48-9) Merck, USA, Digitonin (Cat# D141) Sigma, USA, ACQUITY UPLC BEH Shield RP18 column (Cat#186002854) Water Ltd., ChromXP C18-CL trap column (Cat#5016752) was purchased from Eksigent, ABSciex, USA, nanoViper C18 column (Cat# 164569) Thermo Scientific, USA, Kinetex C18 column (Cat#00B-4601-AN) Phenomenex, USA, Ceramide/Sphingoid Internal Standard Mixture II (Cat# LM6005-1EA) Avanti Polar Lipids, USA, C18 Ganglioside GM3-d3 (d18:1/18:0d3) (ammonium salt) (Cat# 24850) Cayman Chemicals, USA, Ganglioside GM3 (Bovine Milk) (Cat# 860058P) Avanti Polar Lipids, USA, Ganglioside GM1 (Bovine Brain) (Cat# 860065P) Avanti Polar Lipids, USA, Ganglioside GD3 (Bovine Milk) (Cat# 860060P) Avanti Polar Lipids, USA, FITC labeled cholera toxin B (Cat#1,655) Sigma-Aldrich, USA. .. Ceramide Glucosyl transferase (Cat#ab124296) Abcam, UK, Ceramide Glucosyl transferase IHC (Cat# ab197369) Abcam, UK, Ceramide Glucosyl transferase (Cat# 12869-1-AP) ProteinTech, USA, GBA1 (Cat# ab88300) Abcam, UK, eIF4EBP1 (Cat# ab32024) Abcam, UK, P-eIF4EBP1 (Cat# ab75767) Abcam, UK, DNMT1 (Cat# ab188453) Abcam, UK, DNMT1 (Cat# MA5-16169) Invitrogen, USA, H3K4ME3 (Cat# ab1791) Abcam, UK, H3 (Cat# ab8580) Abcam, UK, Rictor (Cat# 2140S) Cell Signaling, USA, Raptor (Cat# 2280) Cell Signaling, USA, Akt (Cat# 4685) Cell Signaling, USA, P- Akt (Cat# 4060) Cell Signaling, USA, P-SGK1 (Cat# 5599) Cell Signaling, USA, P70 Kinase (Cat# 5599) Cell Signaling, USA, ZFX (Cat# 5419) Cell Signaling, USA, ZFX (Cat# PA5-78234) Abcam, UK, JARID1A (KDM5A) (Cat# 3876S) Cell Signaling, USA, KDM5A (Cat# ab70892), Abcam, UK, Phosphoserine (Cat# ab9332) Abcam, UK, EGFR (Cat# 2232) Cell Signaling, USA, P-EGFR (1068) (Cat# 2232) Cell Signaling, USA, P-EGFR(1178) (Cat# 2234) Cell Signaling, USA, Erk1/2 (Cat# 9102S) Cell Signaling, USA, P- Erk1/2 (Cat# 9101) Cell Signaling, USA, Anti-ceramide antibody (Cat# C8104) Sigma, USA, GM3 Synthase (ST8SIA-V) (Cat# sc-365329) Santa Cruz, USA, B3GALT4 (Cat# ab169759) Abcam, UK, GM2/GD2 Synthase (B4GALNT1) (Cat# sc-376505) Santa Cruz, USA, NEU1 (Cat# 67032-1-Ig) ProteinTech, USA, NEU2 (Cat# 24523-1-AP), ProteinTech, USA, NEU3 (Cat# 27879-I-AP), ProteinTech, USA, NEU4 (Cat# 12995-I-AP) ProteinTech, USA, HEXA (Cat# 60337-I-Ig) ProteinTech, USA, HEXB (Cat# 16229-I-AP), ProteinTech, USA, GLA (Cat# 66121-I-Ig), ProteinTech, USA, GLB (Cat# 66586-I-Ig) ProteinTech, USA, β-actin, (Cat# A5441), Sigma, USA, β-actin (Cat# 66009-1-Ig), ProteinTech, USA, Secondary IgG anti-mouse Alexa fluor 594 (Cat# 88903) Cell Signaling, USA, FITC anti-mouse IgM (Cat# 406506) BioLegend, USA, Goat anti-mouse IgG (L+H) (Cat#ab6789) Abcam, UK, Goat anti-rabbit IgG-HRP (Cat# sc-2004) Santa Cruz, USA, Rabbit IgG isotype control (Cat# 02-6102), Invitrogen, USA, Mouse IgG2a Isotype Control (Cat# 02-6200) Invitrogen, USA.



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